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Main > Kidney Disease > Chronic Kidney Disease > CKD Basics >
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How Is Hypertension Associated with Chronic Kidney Disease

2012-09-25 17:21

Before explaining the relationship between high blood pressure (hypertension) and CKD (Chronic Kidney Disease), its classification should be made clear.

Classification of BP levels (according to ESH/ESC-2007)

Classification Systolic BP (mmHg) Diastolic BP (mmHg)
Optimal BP level
<120 <80
Normal 120-129 80-84
High normal
130-139 85-89
Grade 1 (mild)
140-159 90-99
Grade 2 (moderate)
160-179 100-109
Grade 3 (severe)
≥180 ≥110

So, what is the relationship between kidneys and high blood pressure?

High blood pressure would get many vital organs involved inducing plenty of diseases. Organs involved may include kidneys (Chronic Kidney Disease accounts for 10% of all cases), brain (cerebral vascular disease accounts for 10%-15%) and heart (cardiovascular disease accounts for 50%). Generally, kidneys get damaged along with the progression of elevated blood pressure after 15-20 years. Compared with cerebral or cardiovascular disease, Chronic Kidney Disease presents mild symptoms which explain why it is easily to be ignored.

How hypertension gets kidneys involved?

Kidneys are the most dangerous organs that are easily to be injured among patients with elevated blood pressure. Kidney disease induced by high blood pressure called hypertensive nephropathy. It usually describes kidney damages caused by primary hypertension. Reliable data collected reveals that in patients with elevated blood pressure, 20.87% of them may suffer from kidney impairment; while in those without high blood pressure, only 7.43% would possibly develop Chronic Kidney Disease. It is also proved that to lower BP could reduce the incidence rate of ESRD or CKD significantly. For instance, if one’s blood pressure is lowered down 2-15mmHg, incidence rate of ESRD would reduce 35%. If BP reduces more than 20mmHg, then 60% of the incidence rate would be decreased.

Clinical symptoms of hypertension induced CKD

Concentration of renal tubulus becomes abnormal in the initial stage. Symptom in this stage presents frequent urination especially at night. Abnormalities are revealed in patients’ urine as people live with long-standing high blood pressure. As the disease progresses, cardiovascular diseases attack accordingly. CKD appears normally after 10-15 years of increased BP. Mild anemia shows up indicating the disease requires treatment now. But if failed, Renal Failure or ESRD occurs consequently.

All in all, hypertension and Chronic Kidney Disease affects and aggravates each other. Preventing increased BP becomes an effective way to stop the occurrence of CKD.

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Tag: CKD CKD Basics

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