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Main > Kidney Disease > Diabetic Nephropathy > Diabetic Nephropathy Basics >
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Risk Factors of Diabetic Nephropathy

2012-09-30 08:55

Diabetic Nephropathy is one typical complication of Diabetes. It is characterized by hyperfiltration of glomeruli, and then small amount of albuminuria, clinical proteinuria and then ESRD in the end. Pinpointing the risk factors of DN greatly helps its occurrence.

No matter Type 1 Diabetes or T2DM, the incidence rate increases as long as their sisters or brothers suffer from kidney problems induced by Diabetes. Genetic susceptibility and high blood sugar directly result in the occurrence of DN. Other factors, of course, including high blood fat and high blood pressure etc. lead to DN too, but not as important as high blood glucose. According to the report reveals that around 30% of Diabetes patients would suffer from DN somehow, but others won’t no matter what.

Diabetic Nephropathy usually attacks 10 to 15 years later after onset of Diabetes. And also from this report, we found out that the duration of DM is closely associated with DN which makes it become one risk factor. For instance, type 2 Diabetes patients live with more and more complications along with its duration. Once proteinuria occurs, high blood pressure develops accordingly. Compared with those who don’t live with high blood pressure, those who have hypertension are more prone to form Diabetic Nephropathy in a short time.

Lipid metabolism disorder is one independent risky factor. It could lead to hyperfiltration of glomeruli and aggravate kidney impairment among diabetics. Additionally, massive proteinuria loss once attacks, even though their blood sugar is controlled well afterwards, Renal Failure can’t be stopped from happening. Therefore, taking good control of blood sugar and preventing albuminuria from attacking could help prevent Diabetic Nephropathy from happening.

All in all, high blood sugar, duration, genetic factors, high blood pressure and lipid metabolism disorders etc. become risk factors of DN. Thereby, measuring blood glucose, lowering high blood fat and reducing high blood pressure could slow down the progression of Diabetic Nephropathy.

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