Early Stages of Diabetic Nephropathy
Diabetic Nephropathy, just like any other kidney problems, has no signs in the early stage. If the screen of DN is missed, one might be told he or she has this problem only in the late stage. If you have Diabetes, you had better keep an eye open for your kidneys.
In the first stage of Diabetic Nephropathy, one’s kidneys grow much bigger than normal. The poor kidneys have to work extremely hard so as to remove extra sugar from the body.
In the second stage, no symptom is showed up so urinalysis is unable to detect Diabetic Nephropathy. Blood pressure might increase for some degree sometimes, but the fluctuated blood pressure can be nothing to do with kidney problems. However, if the patients take kidney biopsy, there’s change in their kidneys already.
Elevated blood pressure appears frequently, this is because kidney impairment gets blood pressure involved and meanwhile, hypertension leads to kidney damages in return. Protein in urine comes into being at this time, but still, patients feel nothing. This is the most critical phase for DN patients, once they miss to receive treatments in this phase, the disease can’t be reversed.
Proteinuria is one clue for detecting early kidney impairment in Diabetes patients. Compared with albuminuria, microalbuminuria is much reliable. Microalbuminuria becomes the most important as well as best index for DN patients.
If the patients suffer from large amount of proteinuria, he or she has probably progressed into the fourth phase of DN. Blood pressure keeps increasing and urea nitrogen and creatinine begin to elevate. Accumulated toxins and metabolic products in the blood injure various organs like heart or brain. Kidney keeps declining if no treatment is taken in this stage.
The last stage of Diabetic Nephropathy is called chronic renal insufficiency. Elevated blood pressure, edema, oliguria, backache or anemia etc. would develop consequently. There’s almost no chance to reverse the illness condition because it is too late.