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Why Do You Get The Diabetic Nephropathy

2018-08-23 14:43

To most patients they always don’t know the exact reasons why they get the diabetes and nephropathy,that also affect their understanding ot the kidney condition,in order to help them get more reasonable treatment,i will show you the detailed information about the cause of diabetic nephropathy as following:

1. genetic factors: .. Through clinical investigation, it can be found that most Diabetes patients will not develop renal disease eventually, and some patients with good long-term glycemic control can also develop diabetic nephropathy. Glucose transporter – 1 (GLUT1) is the main glucose transporter on glomerular mesangial cells.

The difference in GLUT1 menu attainment and regulation of mesangial cells among different individuals in diabetes may be one of the factors that some patients are prone to kidney damage, which may also be one of the causes of diabetic nephropathy.

2. hyperglycemia: It is also a direct cause of diabetic nephropathy that cannot be ignored. A large number of clinical cases show that the occurrence of diabetic nephropathy is closely related to hyperglycemia. Poor glycemic control can accelerate the development of diabetic nephropathy, and good glycemic control can obviously delay its development. Increased production of hyperglycemia and glycation end products causes mesangial cell proliferation, increased extracellular matrix, mesangial expansion, and thickening of glomerular basement membrane.

In addition, the following life factors may also induce diabetic nephropathy:

1. improper diet and irregular diet have also become the causes of diabetic nephropathy.

2. mental tension and internal disturbance. Diabetes is a persistent disease with a long course of disease. The patients are under high psychological pressure or are nervous, emotional or depressed, which causes the disease to worsen and cost the disease.

3. Overwork leads to gas consumption. Overwork leads to deficiency of vital qi and loss of spleen and kidney, which leads to the accumulation of pathogenic toxin. Overwork includes overwork and hypomotility. Generally there are overwork first, manifested as emaciation, loss of essence and blood, or sex excessiveness, which damages the kidney and exhausts the qi, causing deficiency of the kidney. After that, there will be hypomotility, manifested as unwilling for exercise, did not eat well, gained weight, consumed more gas, or became more ill due to obesity.

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Tag: Diabetic Nephropathy Hyperglycemia Genetic factors Overwork Improper diet Mental tension

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