About Us | Contact Us | Favorite | Mobile version | App DownLoad | Sitemap
Featured StoryAsk a Doctor

Live chat with nephrologists for a free second opinion on your specific illness condition!Ask Dr.Shan

Featured StoryCheck your Kidneys

Take a quick glance at to see if you are at high risks of some sort of kidney problems, such as Renal Failure, Diabetes or PKD etc. Our practical tips help you prevent or treat the disease.GFR Calculators .

Advanced Medical Inspection Equipments

The accurate diagnosis can be a powerful guarantee for the kidney disease treatment While the accurate dialysis needs the support from the advanced medical inspection equipments which achieve world-class level. More Equipment

Patients Blog

It is such a place where you can share your experience, see the international news about kidney disease and find the answers to the questions bothering.

Hospital InformationKidney disease hospital in China

Since 1986, Shijiazhuang Kidney Disease Hospital of China has been dedicated to providing the highest quality care to Kidney Disease patients all over the world.Learn more about Chinese hospitals.

Printer-friendly:

Check your Kidneys

Questions?
Find a doctor

Explore treatments

Related Topic About Kidney Disease
Special Tests for Your Kidneys
Ask a Doctor

Consult or get to know Dr.Shan of the Internal Medicine / nephrology department for free >>

Most Popular Articles
Latest News
Main > Kidney Disease > Nephritis >
Font Size A A A

The Prognosis of Membranoproliferative Glomerulonephritis (MPGN)

Prognosis of Membranoproliferative GlomerulonephritisWith the characteristics of mesangial cell proliferation and structural changes in glomerular capillary walls, Membranoproliferative Glomerulonephritis (MPGN) is divided into three types: I, II and III. Different types have various prognosis of Membranoproliferative Glomerulonephritis (MPGN). Here, we will respectively introduce the prognosis of these three types according to their characteristics.

The prognosis of Type I MPGN

With the immune complexes depositing in the glomerular capillary endothelium, the diffuse thickening and duplication of glomerular basement membrane will occur. Besides, Type 1 MPGN usually companies with chronic or progressive renal insufficiency. In the early stage, patients’ condition develops very slowly, but the speed of condition deteriorating will increase after 5 years. 5%~20% of patients with Type 1 MPGN can be remitted, while most ones will develop renal failure finally. High blood pressure, kidney function decrease, crescents formation, Nephrotic Syndrome, etc, all can worse the prognosis of Membranoproliferative Glomerulonephritis.

The prognosis of Type II MPGN

The glomerular changes in Type II are quite different from Type I. As a lot of immune complexes build up in the glomerular basement membrane, the change presents glomerular basement membrane diffuse thickening. Therefore, Type II MPGN is also called dense deposit disease (DDD). The prognosis of Type II MPGN is worse when patients have high blood pressure, anemia, more than 20% crescents formation and Nephrotic Syndrome, while the prognosis will be relatively better.

The prognosis of Type III MPGN

The pathogenesis of Type III MPGN, which usually has abnormal complement system, is very similar to the one of Type I MPGN. The prognosis of this type MPGN is not very good, but better than Type I MPGN and DDD. The recurrence rate of kidney transplant in this stage is 80%~90%.

Since prognosis of Membranoproliferative Glomerulonephritis including Type I, Type II and Type III, is not very well, patients should take correct treatment timely. Any follow-up questions can be asked, through consulting online or writing down the form below.

Tag: Nephritis

Previous:The Efficient Treatment for Mesangial Proliferative Glomerulonephritis

Next:Low Blood Count Caused by Chronic Glomerulonephritis

Any questions? Fill the form below. You will surely get the free medical advice from experts within 24 hours.

Name:
Country:
Email:
Phone Number:
Skype:
Whatsapp:
Viber:
Disease Description:
 
Related Articles