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Main > Kidney Disease > Renal Failure > Renal Failure Symptoms >
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The Changing Urine Output Can Reflect Your Kidney Condition

2018-12-07 10:26

To common person the certain quantity urine in everyday is normal,but as your kidney function has been damaged then decreased urine output may occur,that is the sign of kidney failure?

Many patients with renal failure said they had symptoms of oliguria. Is oliguria an early sign of renal failure? What should we pay attention to? ..

Normal people’s daily intake of water is equal to that of discharged water, about 2500 ml, with an average daily urine volume of 1500 ml. If the daily urine volume of patients with kidney disease is less than 400 ml, it is ” oliguria” and less than 100 ml is ” anuria”.

Metabolic wastes such as creatinine, urea nitrogen and creatine in human body are mainly discharged from urine. Generally speaking, each person produces 35g of metabolic nitrogen waste every day, and 15ml of urine is needed to dilute each gram of waste. Therefore, the minimum effective urine volume per day should be 500 ml. The higher the protein content, the more urine is needed to eliminate metabolic wastes. When oliguria or no urine occurs, excessive waste in the body accumulates and causes poisoning symptoms.

For chronic renal failure, the kidney itself has been seriously damaged, so it should be reasonable when taking medicine. If the medicine cannot be discharged smoothly from urine, poisoning symptoms may also occur. Therefore, patients with renal failure should be cautious when taking medicine, and doctors should adjust according to the different conditions of patients. Seventy percent of the drugs used in clinic are completely or partially excreted through the kidney. Therefore, changes in renal function will inevitably lead to changes in kinetics and pharmacodynamics. It is very important for patients with renal failure to correctly adjust the dosage of drugs.

The amount of drugs used in chronic renal failure should be reduced according to the slow down of the clear rate of drugs, but the effective concentration in the blood should be guaranteed. Should be paid attention to:

1. Understand the characteristics of commonly used drugs with dynamics and pharmacodynamics;

2. Understand the renal function and other pathophysiological conditions of the patients in detail;

3. Familiarize yourself with the methods of medication when renal insufficiency occurs, and prefer drugs with relatively low renal toxicity.

4. If nephrotoxic drugs are indeed used, the drug dosage should be reduced according to the corresponding methods.

5. Adjust the dosage of some drugs, especially those excreted through the kidney by prototype, according to the degree of renal dysfunction, and use them individually;

Finally, we should carefully observe the illness, find out the adverse reactions in time and deal with them properly.

If a patient with kidney disease suddenly shows symptoms of oliguria or anuria, the condition is usually serious, which is a sign of acute renal failure. This kind of situation is often seen in acute hypovolemic renal azotemia, acute urinary tract obstruction and renal failure.

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Tag: Renal Failure Urine output Oliguria Anuria

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