Blood Purification Technics2012-09-11 14:02
Blood purification introduces patients’ blood out of their bodies and purifies through professional device to eliminate toxins, metabolin, antibodies, immune complexes or other pathogenic substances from blood; by doing so, to treat kidney diseases and some other diseases.
There are several approaches included; they are hemodialysis, hemoperfusion, plasma exchange, immunoadsorption and others. Among all those approaches, hemodialysis takes advantage of dispersion, while hemoperfusion and immunoadsorption utilize adsorption to remove those pathogenic substances. Plasma exchange aims at replacing pathogenic parts with healthy plasma.
What’s the point of doing so?
This is because different molecular substances are suitable for diverse blood purification technics. For those small molecular substances, hemodialysis could do a good job. But immunoadsorption or hemoperfusion is good at discharging middle molecules or even large molecules.
Indications of hemodialysis include:
Acute Renal Failure
Chronic Renal Failure
Intoxication induced by medications or poison
Its contraindications are patients with:
Shock or low blood pressure
Receiving surgery for no more than 3 days
Extreme high blood pressure
Tumor in advanced stage
Critical illness condition
Hemoperfusion takes effects when patients’ blood is led to external, and then those substances united with protein or lipid (that can’t be cleared out by hemodialysis) are removed by adsorbent substance. The most commonly used adsorbent substances are resins and activated carbon. The treatment is mainly used to remove drugs or poisons from blood in emergency situation; it is also adopted to treat complications of Renal Failure etc. however, hemoperfusion couldn’t eliminate extra fluids from the body and fails to correct electrolyte disorders either.
One thing need you to bear in your mind is that hemoperfusion could just discharge toxins themselves instead of correcting patho-physiologic changes, meaning it works for relieving the symptoms instead of dealing with root causes.
Plasma exchange, known as plasmapheresis, is extracorporeal therapy used for removal, treatment, and return of plasma from blood circulation. The procedure is utilized to treat various disorders such as immune system disorders. It is able to get rid of the following pathogenic factors:
Toxins of uremia
Excessive LDL (low density lipoprotein)
Anti-GBM antibody mediated disease (such as Goodpasture’s Syndrome)
RPGN (Rapid progressive glomerulonephritis)
Renal Failure induced by multiple myeloma
Immunoadsorption works through adsorbent substances to remove those toxins, wastes as well as metabolin from blood.
Patients who receive this therapy have low risk of suffering from infections.
The foreign matters can be removed selectively and specifically.
Different adsorbers will be adopted in patients with different illness.
No effect to your currently taking medications.
Other treatments include hemofiltration or LDL apheresis etc.
What you also want to know:
How can I get this treatment ?
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What is the duration if I receive this treatment in your hospital ?
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